An intelligent advisory system for pre-launch processing

The shuttle system of interest in this paper is the shuttle's data processing system (DPS). The DPS is composed of the following: (1) general purpose computers (GPC); (2) a multifunction CRT display system (MCDS); (3) mass memory units (MMU); and (4) a multiplexer/demultiplexer (MDM) and related software. In order to ensure the correct functioning of shuttle systems, some level of automatic error detection has been incorporated into all shuttle systems. For the DPS, error detection equipment has been incorporated into all of its subsystems. The automated diagnostic system, (MCDS) diagnostic tool, that aids in a more efficient processing of the DPS is described

Determinant of Pertamax Fuel Demand in Purwokerto

This research is aiming to analyze the effect of several factors such as Pertamax price, Pertalite price, income, year of vehicle and vehicle type on Pertamax fuel demand in Purwokerto and analyze which one is the most influencial factors on the Pertamax fuel demand using elasticity test. The data used in this research are primary data taken from 100 respondents all around Purwokerto then analyzed using multiple regression analysis. The result of multiple regression analysis indicated that income and vehicle type have significant effect on Pertamax fuel demand in Purwokerto while the other factors such as Pertamax price, Pertalite price and year of vehicle have no influence on Pertamax demand in Purwokerto. This research also indicated that vehicle type was the most influencial factors on Pertamax demand. From all the result that has been found, the result of regression shows that people in Purwokerto have a tendency to keep putting the quality at any price level set by the government. In this case government have to further intensify massively on advertising on good impact of Pertamax either for machine or environment and expected to improve better performance and quality either in terms of services on each gas station or oil distribution

Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission

<p>Background: Artemisinin-based combination therapy (ACT) for treating malaria has activity against immature gametocytes. In theory, this property may complement the effect of terminating otherwise lengthy malaria infections and reducing the parasite reservoir in the human population that can infect vector mosquitoes. However, this has never been verified at a population level in a setting with intense transmission, where chronically infectious asymptomatic carriers are common and cured patients are rapidly and repeatedly re-infected.</p> <p>Methods: From 2001 to 2004, malaria vector densities were monitored using light traps in three Tanzanian districts. Mosquitoes were dissected to determine parous and oocyst rates. Plasmodium falciparum sporozoite rates were determined by ELISA. Sulphadoxinepyrimethamine(SP) monotherapy was used for treatment of uncomplicated malaria in the contiguous districts of Kilombero and Ulanga throughout this period. In Rufiji district, the standard drug was changed to artesunate co-administered with SP (AS + SP) in March 2003. The effects of this change in case management on malaria parasite infection in the vectors were analysed.</p> <p>Results: Plasmodium falciparum entomological inoculation rates exceeded 300 infective bites per person per year at both sites over the whole period. The introduction of AS + SP in Rufiji was associated with increased oocyst prevalence (OR [95%CI] = 3.9 [2.9-5.3], p < 0.001), but had no consistent effect on sporozoite prevalence (OR [95%CI] = 0.9 [0.7-1.2], p = 0.5). The estimated infectiousness of the human population in Rufiji was very low prior to the change in drug policy. Emergence rates and parous rates of the vectors varied substantially throughout the study period, which affected estimates of infectiousness. The latter consequently cannot be explained by the change in drug policy.</p> <p>Conclusions: In high perennial transmission settings, only a small proportion of infections in humans are symptomatic or treated, so case management with ACT may have little impact on overall infectiousness of the human population. Variations in infection levels in vectors largely depend on the age distribution of the mosquito population. Benefits of ACT in suppressingtransmission are more likely to be evident where transmission is already low or effective vector control is widely implemented.</p&gt

An objective function exploiting suboptimal solutions in metabolic networks

Background: Flux Balance Analysis is a theoretically elegant, computationally efficient, genome-scale approach to predicting biochemical reaction fluxes. Yet FBA models exhibit persistent mathematical degeneracy that generally limits their predictive power. Results: We propose a novel objective function for cellular metabolism that accounts for and exploits degeneracy in the metabolic network to improve flux predictions. In our model, regulation drives metabolism toward a region of flux space that allows nearly optimal growth. Metabolic mutants deviate minimally from this region, a function represented mathematically as a convex cone. Near-optimal flux configurations within this region are considered equally plausible and not subject to further optimizing regulation. Consistent with relaxed regulation near optimality, we find that the size of the near-optimal region predicts flux variability under experimental perturbation. Conclusion: Accounting for suboptimal solutions can improve the predictive power of metabolic FBA models. Because fluctuations of enzyme and metabolite levels are inevitable, tolerance for suboptimality may support a functionally robust metabolic network

THE LEGAL PERSPECTIVE ON CONSUMER PROTECTION OF GENETICALLY ENGINEERED FOOD PRODUCTS IN INDONESIA

The development of science and technology has triggered the use of genetic engineering. Genetic engineering is the transplantation of genes into other genes, both between genes and across genes, to produce valuable products for living creatures. Genetically engineered food products, due to the development of modern biotechnology in the field of genetic engineering technology, have given rise to new legal problems because of the possibility of posing a risk to human health. This research uses a normative juridical approach with an emphasis on secondary data. This research uses doctrinal research methods. The research specifications used are analytical descriptive. The research results show that there is no special legal protection for consumers of genetically engineered food products, because it still refers to consumer protection contained in the UUPK. It should be noted that genetic effects resulting from human genetic engineering need legal protection. Protection and intellectual property rights, where everyone, individually or collectively, must be a consumer of goods and services, so the parties need equal legal protection. Therefore, the responsibility of producers of genetically engineered food products for consumer losses must be able to fulfill the principle of justice because the economic position of producers is higher than that of consumers. By implementing the principle of absolute responsibility, the producer responsibility law will foster an attitude of caution for producers of genetically engineered food products to maintain the quality of their products

Collaboration and Co-Teaching: Librarians Teaching Digital Humanities in the Classroom

Digital Humanities (DH) as an area of engagement with students, staff, and teaching faculty has been rapidly evolving at the University of Kansas Libraries (KU Libraries) over the past several years. As the popularity of DH tools, platforms and methodologies has increased, so has the demand to support and engage teaching faculty with incorporating DH in their courses and with their own research interests. Many academic libraries, including KU Libraries, are both adjusting to and leading this shift, figuring out ways to support digital scholarship for research and teaching, while at the same time gently delineating our roles, responsibilities, and limitations. This chapter will describe three examples of efforts by librarians with subject, instruction, and digital scholarship expertise to provide digital humanities instruction and training to students and faculty, and will look at how these efforts relate to our previous and evolving roles within the library. We will also provide concrete examples of in-class assignments, describe what worked well and what could be improved, and discuss some possible ways that we ourselves might develop the knowledge and skills needed to engage in this kind of work. We hope that these examples and observations can serve as models, starting-points, or inspiration for subject specialists to both learn more about digital humanities and to develop their own course activities

Anxiety, Stress, and Health in Northern Plains Native Americans

In the present study, the Beck Anxiety Inventory (Beck, Epstein, Brown, & Steer, 1988), Anxiety Sensitivity Inventory (Peterson & Reiss, 1992), the Holmes-Rahe Social Readjustment Rating Scale (Holmes & Rahe, 1967), Northern Plains Bicultural Inventory (Allen & French, 1994), and a health questionnaire were administered to investigate the relationship between anxiety, stressful events, health, and cultural participation among 147 Native American adults from a Midwestern reservation community. The results of these self-report measures indicated that, as has been found in the majority culture, stressful life events predicted physical health problems and self-reported anxiety. The hypothesis that participation in and identification with tribal culture would be associated with fewer life stressors, better health, and lower anxiety was not supported. Surprisingly, cultural identification did not buffer the relationship between stressful life events and anxiety. Implications for understanding anxiety and stress among Native Americans are discussed

An NCATE-Approved School of Education Self-Study on Diversity: Faculty and Student Perceptions

Accreditation bodies for institutions of higher education like the National Council for Accreditation of Teacher Education (NCATE) and Western Association of Schools and Colleges (WASC) require colleges and universities to create campus climates and experiences for students that foster diversity